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Vitamin B12 Deficiency And Cancer: Vitamin B12 deficiency is a common health concern, often linked to dietary insufficiencies or malabsorption issues. But can this deficiency signal a more serious condition, such as cancer? We speak to experts with some insights suggesting possible connections, while others refute a direct correlation.

Dr Deepak Jha, Chief of Breast Surgery and Senior Consultant in Surgical Oncology at Artemis Hospitals explains that although a direct link between vitamin B12 deficiency and cancer is not well-established, certain cancers, particularly those affecting the gastrointestinal tract, can impair nutrient absorption. This includes vitamin B12. He elaborates that cancer can increase the body’s metabolic demands, which might exacerbate existing deficiencies.

Some studies have suggested an association between low B12 levels and an increased risk of developing specific cancers. For example, Dr Jha points out that low B12 status has been linked to elevated levels of homocysteine, an amino acid thought to be a risk factor for certain cancers. However, he says that these studies are not conclusive and should not be interpreted as a definitive link between B12 deficiency and cancer development.

In summary, while vitamin B12 deficiency itself is not a direct indicator of cancer, Dr Jha advises that it can be associated with conditions that may increase cancer risk or occur in the context of existing malignancies. Therefore, if someone is experiencing symptoms of B12 deficiency, it is important to seek medical advice for proper diagnosis and management, especially if other concerning signs are present.

On the other hand, Dr Roshan Dikshit, Senior Consultant in Hematology and Bone Marrow Transplant at Aakash Healthcare, provides a straightforward response: “No, vitamin B12 deficiency is not a sign of cancer.” According to Dr Dikshit, while B12 deficiency can cause anaemia, low white blood cell counts, and low platelet counts, it does not directly contribute to the development of cancer.

Dr Dikshit says that although the deficiency may lead to certain blood-related issues, such as anaemia, it should not be viewed as a precursor or indicator of cancer. His message is clear—B12 deficiency alone is not a cause for alarm in terms of cancer risk.

While experts like Dr Jha recognise that certain cancers may influence B12 absorption, the deficiency itself is not a clear indicator of cancer, as clarified by Dr Dikshit. If you suspect you have a vitamin B12 deficiency, it is essential to consult a healthcare provider for appropriate diagnosis and treatment. However, based on current evidence, vitamin B12 deficiency should not be considered a direct sign of cancer.

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